Active Motif,
Tools to analyze nuclear function,
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Protein Detection and Quantitation

Protein Detection and Quantitation

 

The function and activation of many proteins are controlled through post-translational modifications. The addition and/or removal of a variety of functional groups can cause conformational changes that alter a protein's shape, enabling it to bind other proteins or perform other tasks not possible prior to being modified. Phosphorylation, methylation, acetylation, ubiquitination and SUMOylation are just a few of the modifications that are involved in the regulation of protein activity and cell signaling.