CUT&RUN Assay Kits

Target histone modifications or transcription factors genome-wide with less cell input than traditional ChIP

CUT&RUN (Cleavage Under Targets & Release Using Nuclease) is an epigenetic method used to investigate the genome-wide distribution of various chromatin-associated proteins and their modifications. CUT&RUN is a derivative of chromatin immunocleavage (ChIC). CUT&RUN is similar to chromatin immunoprecipitation (ChIP), in that it utilizes an antibody to target chromatin-associated marks and proteins, but requires less sample material and less sequencing depths than ChIP.

Genome-wide chromatin-associated protein profiling from 5,000 to 500,000 cells.

Normalize between CUT&RUN datasets with certainty to identify biological differences.