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ATAC-Seq (Assay for Transposase-Accessible Chromatin) is a rapid and simple method for profiling open chromatin regions genome-wide. Because ATAC-Seq utilizes hyperactive mutant transposase Tn5, NGS adapters are simultaneously integrated while open chromatin regions are fragmented by the transposase, yielding next-gen sequencing-ready libraries without a library preparation step in 1-2 days.
Profile open chromatin regions in formaldehyde-fixed cells.
Pure recombinant Tn5 transposase enzyme in 10 µg, 100 µg or larger quantities.
