AVAILABLE PRODUCTS

LightSwitch™ Promoter and 3’ UTR Collections

Complete luciferase assay system designed for high-throughput functional genomic screens

With a genome-wide library of over 30,000 pre-cloned and ready to transfect regulatory elements, a highly optimized Renilla luciferase (RenSP) vector system and assay reagents, the LightSwitch™ luciferase reporter assay system is the optimal solution for your gene regulation studies. Select from our wide range of products and services below.

Learn more about the LightSwitch™ luciferase reporter assay system

 

 

Search the Pre-Cloned LightSwitch Luciferase GoClone® Collections

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Promoter & Distal Regulatory Element Luciferase Construct Collection

LightSwitch™ Promoter Reporter GoClone Collection

Promoter Reporter GoClone Collection

The promoter reporter collection includes over 18,000 promoters cloned from the human genome and available as transfection-ready GoClone constructs.

LightSwitch™ Promoter Reporter GoClone Collection

lncRNA Promoter Reporter Collection

The lncRNA promoter reporter collection was designed to make it fast and easy to study the regulation of lncRNA promoters.

LightSwitch™ Promoter Controls

Promoter Reporter GoClone Controls

The LightSwitch system contains many positive and negative promoter controls to optimize experimental conditions and normalize for non-specific effects.

LightSwitch™ Synthetic Response Elements

Synthetic Response Element Collection

The synthetic response elements are useful positive controls due to their stronger response compared to endogenous promoter and enhancer sequences.

LightSwitch™ Validated Pathway Collections

Validated Pathway Biomarker Kits

Pathway promoters that were selected based on sequence motif analysis and published data. They show significant activation or repression in response to pathway-specific induction.

miRNA & 3´ UTR Luciferase Construct Collection

LightSwitch™ 3´UTR Reporter GoClone Collection

3´ UTR Reporter GoClone Collection

Our 3´ UTR reporter collection includes over 12,000 3' UTRs cloned from the human genome into ready-to-transfect LightSwitch reporter vectors.

Synthetic miRNA

Synthetic miRNA Targets

The LightSwitch synthetic miRNA target reporters are useful positive controls due to their strong response compared to endogenous 3' UTRs sequences.

LightSwitch™ 3´UTR Control Vectors

3´ UTR Reporter GoClone Controls

The LightSwitch system contains a number of positive and negative 3´ UTR controls to optimize experimental conditions and normalize for non-specific effects.

LightSwitch™ miRNA Mimics & Inhibitors

miRNA Mimics & Inhibitors

With our large collection of miRNA mimics and inhibitors, you have everything needed to study miRNA-3´ UTR interactions, validate miRNA targets, measure RNA stability, translation efficiency, and the functional impact of miRNAs on a gene-by-gene basis.

LightSwitch Luciferase Reporter Assay System Reagents

LightSwitch™ Luciferase Assay Kit

Luciferase Assay Kit

The novel substrate and optimized lysis buffer included in the Luciferase Assay Kit were formulated to provide high sensitivity over a broad dynamic range when used with our engineered RenSP Luciferase.

LightSwitch™ Empty Vector Suite

LightSwitch Empty Vector Suite

Complete list of all LightSwitch vector options together with sequence and annotation files and insert sequencing primers.

LightSwitch™ Transfection Optimization Kit

LightSwitch™ Transfection Optimization Kit

Quickly and easily optimize transfection conditions to achieve best results in your luciferase reporter assays.