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CpG Islands, DNA Methylation, and Disease (Sir Adrian Bird)

Episode 24

June 18, 2020

In this episode of the Epigenetics Podcast, we caught up with Sir Adrian Bird, Buchanan Professor of Genetics at the University of Edinburgh, to talk about his work on CpG islands, DNA methylation, and the role of DNA methylation in human diseases.

In this interview, podcast host Stefan Dillinger and Adrian Bird discuss the discovery of the methyl-CpG-binding protein MeCP2, which is almost as abundant as histones in neurons. MeCP2 deficiencies in children can cause serious neurological diseases such as the autism spectrum disorder Rett Syndrome. Adrian Bird talks about how his research on MeCP2 may potentially lead to the discovery of a treatment for Rett Syndrome.


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