Sonication Products

reproducible sonication for more consistent results

Active Motif’s PIXUL™ and EpiShear™ sonication products are ideal for shearing chromatin, DNA, RNA, and protein for use in chromatin immunoprecipitation (ChIP), DNA methylation studies, next-generation sequencing, and proteomics assays. They were designed to save you time and effort, and include features like arrayed transducers and fully programmable digital generators that give you the control needed to get the most reproducible results possible.


The PIXUL Multi-Sample Sonicator is the first and only multi-sample sonicator that delivers extremely consistent shearing of up to 96 samples processed in parallel and is fast, simple, and inexpensive to operate. PIXUL is compatible with simultaneous processing of 1-96 samples in parallel to avoid sample shearing bottlenecks in NGS applications. Furthermore, up to 12 unique sonication conditions can be run on a single 96-well plate, allowing simultaneous processing of multiple sample types and rapid optimization of conditions for difficult samples. Sonication is carried out in standard and inexpensive 96-well plates, keeping sample processing costs low, and lengthy water degassing steps are not required, saving time. More >

PIXUL Multi-Sample Sonicator
PIXUL™ Multi-Sample Sonicator

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The EpiShear Probe Sonicator offers you the flexibility to shear both small or large sample sizes. With the supplied 1/8" microtip probe, you can process samples from 500 µl to 15 ml. Other probes are available, which increase the range of samples that can be processed to 200 µl up to 50 ml.

A variety of accessories are available for use with the EpiShear Probe Sonicator, including different sizes of microtip probes, a sound enclosure to reduce noise, a converter stand for hands-free use, and a footswitch that makes it more convenient to deliver short pulses when using the unit in manual mode. More >

EpiShear Probe Sonicator and the Cooled Sonication Platform
EpiShear™ Probe Sonicator with
support stand / converter clamp.

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