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Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.
Active Motif also offers several small molecule inhibitors to study the effect of changes in HAT and HDAC activity.
| Name | Appl. | Format | Cat No. | Price | |
|---|---|---|---|---|---|
| Apicidin | HDAC Inhibitor | 5 mg | 14040 | $295 | Add to Cart |
| 1 mg | 14041 | $85 | Add to Cart | ||
| BML-210 | HDAC Inhibitor | 25 mg | 14048 | $275 | Add to Cart |
| 5 mg | 14049 | $75 | Add to Cart | ||
| C646 | p300/CBP Inhibitor | 25 mg | 14052 | $245 | Add to Cart |
| 5 mg | 14053 | $70 | Add to Cart | ||
| CI-994 | HDAC Inhibitor | 25 mg | 14092 | $325 | Add to Cart |
| 5 mg | 14093 | $95 | Add to Cart | ||
| CPTH2 | Gcn5P Inhibitor | 25 mg | 14094 | $325 | Add to Cart |
| 5 mg | 14095 | $95 | Add to Cart | ||
| CTPB | p300 Activator | 25 mg | 14064 | $215 | Add to Cart |
| 5 mg | 14065 | $65 | Add to Cart | ||
| CUDC-101 | HDAC and Receptor Tyrosine Kinase Inhibitor | 25 mg | 14060 | $500 | Add to Cart |
| 5 mg | 14061 | $135 | Add to Cart | ||
| Embelin | PCAF Inhibitor | 50 mg | 14118 | $275 | Add to Cart |
| 10 mg | 14119 | $65 | Add to Cart | ||
| Garcinol | p300/pCAF Inhbitor | 50 mg | 14076 | $385 | Add to Cart |
| 10 mg | 14077 | $95 | Add to Cart | ||
| HPA (Hexyl-4-pentynoic acid) | HDAC Inhibitor | 50 mg | 14034 | $120 | Add to Cart |
| 10 mg | 14035 | $55 | Add to Cart |
