Activators / Inhibitors

small molecules for epigenetic research

Active Motif has a collection of small-molecule epigenetic modulators (activators and inhibitors) that target changes to DNA methylation and chromatin remodeling proteins, such as histones. These include targets to DNA Methyltransferases (DNMTs), Histone Acetyltransferases (HATs), Histone Deacetylases (HDACs), Histone Methyltransferases (HMTs), Histone Demethylases (HDMs) and a distinct set of chromatin readers, bromodomains. As epigenetic dysregulation is implicated in many diseases, these modulators represent important tools for researchers in their assay development and drug discovery initiatives.

A list of the available activators and inhibitors for epigenetic research is shown below. Please click on the small molecule name to view complete product information.

 
Name Appl. Format Cat No. Price  
2'-Deoxy-5-fluorocytidine DNMT Inhibitor 250 mg 14108 $370 Buy
50 mg 14109 $95 Buy
5-Aza-2’-deoxycytidine (Decitabine) DNMT Inhibitor 50 mg 14100 $385 Buy
10 mg 14101 $105 Buy
5-Azacytidine DNMT Inhibitor 250 mg 14102 $85 Buy
50 mg 14103 $25 Buy
6-Thioguanine DNMT Inhibitor 1 g 14126 $125 Buy
100 mg 14127 $35 Buy
AK-7 SIRT2 Inhibitor 25 mg 14054 $260 Buy
5 mg 14055 $65 Buy
Apicidin HDAC Inhibitor 5 mg 14040 $265 Buy
1 mg 14041 $75 Buy
Arecoline hydrobromide ACAT1 Inhibitor 1 g 14132 $85 Buy
250 mg 14133 $35 Buy
AS-8351 KDM5B Inhibitor 25 mg 14112 $200 Buy
5 mg 14113 $50 Buy
BIX-01294 G9a/GLP Inhibitor 25 mg 14072 $450 Buy
5 mg 14073 $100 Buy
BML-210 HDAC Inhibitor 25 mg 14048 $240 Buy
5 mg 14049 $65 Buy