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CUT&RUN (Cleavage Under Targets & Release Using Nuclease) is an epigenetic method used to investigate the genome-wide distribution of various chromatin-associated proteins and their modifications. CUT&RUN is a derivative of chromatin immunocleavage (ChIC). CUT&RUN is similar to chromatin immunoprecipitation (ChIP), in that it utilizes an antibody to target chromatin-associated marks and proteins, but requires less sample material and less sequencing depths than ChIP.
Active Motif specializes in manufacturing high-quality antibodies to histones, histone modifications, chromatin proteins, and other factors, including a growing list of antibodies that we have experimentally validated in-house to work well in CUT&RUN assays.
Active Motif Antibodies Published for Use in CUT&RUN
The following applications have been published using these antibodies and is provided for reference. Active Motif may not have validated these antibodies for use in these applications.
CUT&RUN Publications
The antibodies in the table below have been validated for use in our ChIC/CUT&RUN Assay Kit Click on the antibody name to see its complete information.
| Name | Isotype | Reactivity | Application | Format | Cat No. | Price | |
|---|---|---|---|---|---|---|---|
| BRD2 antibody (pAb) | IgG | Human | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN | 100 µl | 61797 | $530 | Add to Cart |
| 10 µl | 61798 | $130 | Add to Cart | ||||
| BRD3 antibody (pAb) | IgG | Human, Mouse | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN, Western blot | 100 µl | 61489 | $530 | Add to Cart |
| 10 µl | 61490 | $130 | Add to Cart | ||||
| AbFlex® BRD4 antibody (rAb) | IgG | Human | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN | 100 µg | 91301 | $400 | Add to Cart |
| 10 µg | 91302 | $90 | Add to Cart | ||||
| Ets-1 antibody (pAb) | Serum | Human, Mouse | ChIP-Seq, CUT&RUN, Western blot | 100 µl | 39580 | $530 | Add to Cart |
| 10 µl | 39581 | $130 | Add to Cart | ||||
| EZH2 antibody (pAb) | Serum | Human, Mouse | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN, Immunoprecipitation | 100 µl | 39901 | $530 | Add to Cart |
| 50 µl | 39002 | $305 | Add to Cart | ||||
| 10 µl | 39902 | $130 | Add to Cart | ||||
| AbFlex® Histone H3K4me3 antibody (rAb) | IgG2a | Human, Wide Range Predicted | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN, CUT&Tag, Dot blot, Western blot | 100 µg | 91263 | $400 | Add to Cart |
| 10 µg | 91264 | $90 | Add to Cart | ||||
| Histone H3K4me3 antibody (pAb) | Serum | Budding Yeast, Human, Mouse, Wide Range Predicted | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN, CUT&Tag, Dot Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western blot | 100 µl | 39159 | $530 | Add to Cart |
| 50 µl | 39060 | $305 | Add to Cart | ||||
| 10 µl | 39160 | $130 | Add to Cart | ||||
| Histone H3K4me3 antibody (pAb) | IgG | Budding Yeast, Human, Wide Range Predicted | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN, CUT&Tag, Dot Blot, Immunocytochemistry, Immunofluorescence, Western blot | 100 µg | 39915 | $530 | Add to Cart |
| 50 µg | 39016 | $305 | Add to Cart | ||||
| 10 µg | 39916 | $130 | Add to Cart | ||||
| AbFlex® Histone H3K27ac antibody (rAb) | IgG2a | Human, Wide Range Predicted | ChIP-Seq, CUT&RUN, CUT&Tag, ELISA, Western blot | 100 µg | 91193 | $400 | Add to Cart |
| 10 µg | 91194 | $90 | Add to Cart | ||||
| Histone H3K27me3 antibody (pAb) | IgG | Human, Mouse, Wide Range Predicted | ChIP-Seq, Chromatin Immunoprecipitation, CUT&RUN, CUT&Tag, Dot Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western blot | 100 µg | 39155 | $530 | Add to Cart |
| 50 µg | 39055 | $305 | Add to Cart | ||||
| 10 µg | 39157 | $130 | Add to Cart |
