Recombinant METTL19 (TRMT44) protein

Catalog No: 81088 Format: 20 µg $405 Buy
Catalog No: 81788 Format: 1 mg $3,600 Buy
Expressed In: Baculovirus Protein Species: Human

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Contents

Recombinant METTL19 (TRMT44) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100 and 0.5 mM TCEP. Please refer to product insert upon arrival for lot-specific concentration.

Background

METTL19 (Methyltransferase-Like Protein 19), also known as TRMT44 (TRNA Methyltransferase 44 Homolog), is a putative tRNA methyltransferase found in the cytoplasm. It has a probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase activity. Defects in METTL19 gene may be associated with partial epilepsy with pericentral spikes (PEPS).

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.

Protein Details

Recombinant human METTL19 (TRMT44) protein was expressed in a baculovirus expression system as the full length protein (accession number NP_689757.2) with an N-terminal FLAG tag. The molecular weight of the protein is 85.8 kDa.

 
Recombinant METTL19 (TRMT44) protein gel

Recombinant METTL19 (TRMT44) protein gel
10% SDS-PAGE Coomassie staining
MW: 85.8 kDa
Purity: >75%

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is guaranteed for 6 months from date of arrival.