CTPB

Aliases: N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide
Catalog No: 14064 Format: 25 mg $200 Buy
Catalog No: 14065 Format: 5 mg $55 Buy
Application: Histone Acetylation (HAT & HDAC)

Chemical Properties

MW = 554.1
C31H43ClF3NO2
CAS 586976-24-1
98% (TLC; 1:10 EtOAc:Hexane; Rf = 0.26); NMR (Conforms)

Description

A selective activator of p300 HAT (histone acetyltransferase). Selective over PCAF (p300 CPB-associated factor) (ref 1, 2).

Contents

Off white powder. May be dissolved in DMSO (100 mg/ml); Ethanol (50 mg/ml).

Storage Conditions

Store desiccated as supplied at -20°C for up to 3 years. Store solutions at -20°C for up to 3 months.

References

1. K Balasubramanyam et al. J. Biol. Chem. 2003, 278:19134
2. K Mantelingu et al. J. Phys. Chem. 2007, 111:4527

 
Chemical structure of CTPB.

Chemical structure of CTPB.