MEIS 1/2/3 antibody (mAb)

RRID: AB_2750570
Clone: 9.2.7
Catalog No: 39795 Format: 100 µg $510 Buy
Catalog No: 39796 Format: 10 µg $125 Buy
Catalog No: 39096 Format: 50 µg $295 Buy

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Antibody Type:
Monoclonal
Isotype:
IgG1
Purification:
Protein A Chromatography
Host:
Mouse
Molecular Weight:
54-66 kDa
Reactivity:
Human, Mouse

Applications

Immunofluorescence Validated Immunocytochemistry Validated

Application Notes

Applications Validated by Active Motif:
ICC/IF: 0.5 µg/ml dilution

This antibody is also available as an AbFlex® engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91259.

Published Applications

The following applications have been published using this antibody. Unless noted above, Active Motif may not have validated the antibody for use in these applications:

IF

View publications that use Active Motif products & services here. Enter the product number(s) to see publications & applications that use this antibody.

Immunogen

This MEIS antibody was raised against a recombinant protein corresponding to amino acids amino acids 50-390 mouse MEIS1.

Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

 

MEIS 1/2/3 antibody (mAb) tested by Immunofluorescence.
Formaldehyde fixed HeLa cells stained with MEIS 1/2/3 antibody at a 0.5 µg/ml dilution.

Background

The MEIS family or proteins (Myeloid Ecotropic viral Integration Site homologues) encode proteins that function as cofactors for the Homeobox (HOX) proteins. Homeobox genes play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. MEIS and a functionally related protein Pbx belong to the TALE (Three Amino acid Loop Extension) homeodomain superfamily of proteins. The role of MEIS proteins in the regulation of transcription is as yet unclear.

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Guarantee

This product is guaranteed for 12 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • WB = Western Blotting