HSC70 / HSP7C antibody (mAb)

RRID: AB_2793552
Clone: 6E1
Aliases: HSPA8, LAP1, HSC54, HSC71, HSP71, HSP73, NIP71, HEL-33, HSPA10, HEL-S-72p
Catalog No: 61207 Format: 100 µg $320 Buy
Catalog No: 61208 Format: 10 µg $105 Buy

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Antibody Type:
Monoclonal
Isotype:
IgG2a
Purification:
Protein G Chromatography
Host:
Rat
Molecular Weight:
70 kDa
Reactivity:
Human

Applications

Western Blot Validated Immunoprecipitation Validated Immunofluorescence Validated Immunocytochemistry Validated

Published Applications

The following applications have been published using this antibody. Unless noted above, Active Motif may not have validated the antibody for use in these applications:

IP
ICC/IF
WB

View publications that use Active Motif products & services here. Enter the product number(s) to see publications & applications that use this antibody.

Immunogen

This HSC70 / HSP7C antibody was raised against full-length recombinant human HSC70 / HSP7C protein.

Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

Background

HSC70 / HSP7C (Heat Shock Cognate 70, HSP73, Heat Shock Protein 73) is a member of the DnaK/HSP70 family of protein chaperones involved in protein homeostasis. HSC70 is constitutively expressed and essential for cell viability and functions both in preventing or reversing protein aggregation and in disassembling protein complexes. HSC70 predominantly binds non-native polypeptides and folding intermediates that are either newly synthesized or stress-induced.

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Guarantee

This product is guaranteed for 12 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • WB = Western Blotting