Recombinant MAX protein, His-Tag

Catalog No: 81026 Format: 100 µg $405 Buy
Catalog No: 81726 Format: 1 mg $2,600 Buy
Expressed In: E. coli Protein Species: Human

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Contents

Recombinant MAX protein, His-tag is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10% glycerol and 0.5 mM TCEP. 

Background

MAX (MYC Associated Factor X, also known as BHLHd4) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5-CAC[GA]TG-3. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 Lys-9 histone methyltransferase activity. 

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.

Protein Details

Recombinant MAX protein, His-tag was expressed in E.coli cells as the full length protein (accession number NP_660087.1) with an N-terminal 6×His tag. The molecular weight of this protein is 20.7 kDa. 

 
Recombinant MAX protein, His-tag, protein gel.

Recombinant MAX protein, His-tag, protein gel
12.5% SDS-PAGE Coomassie staining
MW: 20.7 kDa
Purity: > 85%

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.