BML-210

Aliases: N1-(2-aminophenyl)-N8-phenyloctanediamide
Catalog No: 14048 Format: 25 mg $240 Buy
Catalog No: 14049 Format: 5 mg $65 Buy
Application: Histone Acetylation (HAT & HDAC)

Chemical Properties

MW = 339.4
C20H25N3O2
CAS 537034-17-6
MP = 168-170°C
98% (TLC); NMR (Conforms)

Description

A novel non-hydroxamic HDAC inhibitor. (IC50 = 5-10 M) (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.

Contents

Tan powder. May be dissolved in DMSO (25 mg/ml); Ethanol (10 mg/ml, warm).

Storage Conditions

Store desiccated as supplied at 4°C for up to 2 years. Store solutions at -20°C for up to 3 months.

References

1. J Savickiene et al. Eur. J. Pharmacol. 2006, 549:9
2. D Herman et al. Nature Chem. Biol. 2006, 10:551

 
Chemical structure of BML-210.

Chemical structure of BML-210.