Recombinant RanGAP1 protein

Aliases: Ran GTPase- activating protein 1,
Catalog No: 82104 Format: 50 µg $470 Add to Cart
Catalog No: 82704 Format: 1 mg $2,950 Add to Cart

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Expressed In: E. coli Protein Species: Human

Contents

A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.

Background

RanGAP1 (Ran GTPase-activating protein 1) is a GTPase activator for RAN. Converts cytoplasmic GTPbound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export. Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export.

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product.  All available data for this product is shown. 

Protein Details

Recombinant RanGAP1 protein that includes full length of human RanGAP1 protein (accession number NP_001265580.1) was expressed in E. coli and contains an N-terminal GST tag with a molecular weight of 90.37 kDa. The purity of the protein is ≥ 75% by SDS-PAGE.

 

Recombinant RanGAP1 protein gel
10% SDS-PAGE gel
MW: 90.37
Purity: >75%

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.