Recombinant NSUN6 protein
|Catalog No: 81174||Format: 20 µg||$430||Buy|
|Catalog No: 81874||Format: 1 mg||$3,840||Buy|
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Expressed In: Baculovirus Protein Species: Human
A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.
NSUN6 (NOP2/Sun Domain Family, Member 6), also called as NOPD1, is a member of NSUN family. It may have S-adenosyl-L-methionine-dependent methyl-transferase activity. Recently, researches found that human NSUN6 is associated with tRNAs and acts as a tRNA methyltransferase. It may play a major role in bone metastasis through the methylation of Hippo/MST1 and consequent activation of YAP, implying that NSUN6 could be a valuable target for bone metastasis and therapy-resistant oncology research
This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Recombinant NSUN6 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_872349.1) with an N-terminal FLAG tag. The molecular weight of the protein is 53 kDa.
Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.