Recombinant DDX5 protein

Aliases: Probable ATP-dependent RNA helicase, G17P1, HLR1, P68, DEAD Box Proteins
Catalog No: 82125 Format: 20 µg $505 Add to Cart
Catalog No: 82725 Format: 1 mg $4,500 Add to Cart

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Expressed In: Baculovirus Protein Species: Human

Contents

A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.

Background

DDX5 (Probable ATP-dependent RNA helicase DDX5) encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes because of its role as an adaptor molecule, promoting interactions with many other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants.

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.

Protein Details

Recombinant DDX5 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_004387.1) with an N-terminal FLAG tag. The molecular weight of DDX5 is 70.42 kDa.

References

Human

 
Recombinant DDX5 protein

Recombinant DDX5 protein
10% SDS-PAGE gel with Coomassie blue staining
MW: 70.42 kDa
Purity: >90%

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is guaranteed for 6 months from date of arrival.