Recombinant DDX1 protein

Aliases: DDX1, DEAD-Box Helicase 1
Catalog No: 82165 Format: 20 µg $480 Add to Cart
Catalog No: 82765 Format: 1 mg $4,150 Add to Cart

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Applications

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product.  All available data for this product is shown. 

References

Human

 
Recombinant DDX1 protein gel

Recombinant DDX1 protein gel
4-20% SDS-PAGE gel
MW: 84.13 kDa
Purity: >95%

Background

DDX1 is a highly conserved ATP-dependent RNA helicase crucial for multiple aspects of RNA metabolism, including transcription, splicing, and export. It plays a vital role in resolving R-loops to maintain genomic stability and is a core component of the tRNA splicing machinery. Importantly, DDX1 is frequently amplified and overexpressed in various cancers, where it promotes tumor growth, therapy resistance, and viral replication, making it a significant factor in oncology and a potential therapeutic target.

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • TIP-ChIP = Tagmented, Indexed, and Pooled Chromatin Immunoprecipitation;
  • WB = Western Blotting