Sox11 antibody (pAb)

Aliases: SRY-Box 11
Catalog No: 61181 Format: 100 µl $435 Buy
Catalog No: 61182 Format: 10 µl $105 Buy

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Antibody Type:
Polyclonal
Isotype:
IgG
Purification:
Affinity Purified
Host:
Rabbit
Molecular Weight:
65 kDa
Reactivity:
Human

Applications

Western Blot Validated

Application Notes


Validated Applications:
WB: 1:500 - 1:1,000 dilution

Immunogen

This Sox11 antibody was raised against a peptide from the N-terminus of human Sox11.

Buffer

Purified rabbit IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

References

 
Sox11 antibody (pAb) tested by Western blot.

Sox11 pAb tested by Western blot.
Nuclear extract of Y-79 cells (20 µg) was probed with Sox11 pAb (1:500 dilution).

Background

Sox11 (SRY-box containing protein 11) is a member of a family of transcription factors containing an HMG DNA-binding domain. Sox11 is important for the development of nervous system. Sox11 is upregulated in a variety of tumor types, including medulloblastomas, gliomas and epithelial ovarian tumors. In B cell lymphomas, information regarding the expression of Sox11 aids in diagnosis and prognosis. Sox11 also functions as a tumor suppressor in glioma-initiating cells.

Positive Control

Active Motif's Y-79 nuclear extract (Catalog No. 36064) can be used as a positive control for Sox11 antibody.

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting