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Recombinant DDX6 protein
| Aliases: Probable ATP-dependent RNA helicase DDX6 |
| Catalog No: 82126 | Format: 20 µg | $505 | Add to Cart |
| Catalog No: 82726 | Format: 1 mg | $4,500 | Add to Cart |
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Expressed In: Baculovirus Protein Species: Human
Contents
A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.
Background
DDX6 (Probable ATP-dependent RNA helicase DDX6), Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.
Application Notes
This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for this product is shown.
Protein Details
Recombinant DDX6 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_004388.2) with an N-terminal FLAG tag. The molecular weight of DDX6 is 55.69 kDa.
Recombinant DDX6 protein gel
10% SDS-PAGE gel
MW: 55.69
Purity: >95%
Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Guarantee
This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.
