Recombinant DHX9 protein

Aliases: DEAD box helicase family
Catalog No: 82164 Format: 20 µg $480 Add to Cart
Catalog No: 82764 Format: 1 mg $4,150 Add to Cart

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Applications

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.

References

Human

 

Recombinant DHX9 protein
4 - 20% SDS-PAGE gel and stained with Coomassie blue.
MW: 142.23 kDa
Purity: >95%

Background

DHX9 is a multifunctional nuclear ATP-dependent RNA helicase crucial for resolving complex nucleic acid structures. It plays essential roles in transcription, mRNA processing and export, translation, and genomic stability by unwinding DNA/RNA hybrids (R-loops) and structured RNAs. Its activity is vital for viral replication, and dysregulation of DHX9 is implicated in cancer development, neurodegenerative diseases, and autoimmune disorders, highlighting its importance as a central node in nucleic acid metabolism.

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • TIP-ChIP = Tagmented, Indexed, and Pooled Chromatin Immunoprecipitation;
  • WB = Western Blotting