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Recombinant GNMT protein
| Aliases: Glycine N-Methyltransferase |
| Catalog No: 81301 | Format: 50 µg | $450 | Buy |
| Catalog No: 81601 | Format: 1 mg | $3,000 | Buy |
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Expressed In: E. coli Protein Species: Human
Contents
A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.
Background
GNMT (Glycine N-Methyltransferase) is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homo-tetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants.
Application Notes
This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Protein Details
Full length human GNMT protein was expressed in E. coli cells (accession number NP_061833.1) with a C-terminal 6xHis Tag. The molecular weight of the protein is 34.9 kDa.
Recombinant GNMT protein gel
10% SDS-PAGE with Coomassie blue staining
MW: 34.9 kDa
Purity: >95%
Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Guarantee
This product is guaranteed for 6 months from date of arrival.
