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Recombinant G6PD protein
| Aliases: Glucose-6-phosphate dehydrogenase |
| Catalog No: 81299 | Format: 50 µg | $450 | Buy |
| Catalog No: 81999 | Format: 1 mg | $3,000 | Buy |
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Expressed In: E. coli Protein Species: Human
Contents
A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.
Background
G6PD (Glucose-6-Phosphate Dehydrogenase) is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.
Application Notes
This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Protein Details
Full length human G6PD protein was expressed in E. coli cells (accession number NP_001035810.1) with a C-terminal 6xHis Tag. The molecular weight of the protein is 60.3 kDa.
Recombinant G6PD protein gel
10% SDS-PAGE with Coomassie blue staining
MW:60.3 kDa
Purity: >90%
Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Guarantee
This product is guaranteed for 6 months from date of arrival.
